Resource Library

FHI360 TLD briefer

Tenofovir, Lamivudine, and Dolutegravir (TLD) Transition

FHI360, 2019

The World Health Organization (WHO) has recommended that all countries using TLE as a first-line regimen should transition all eligible clients to a different combination, which contains dolutegravir (DTG) in place of efavirenz—that is, TLD, with the “D” standing for dolutegravir. This recommended regimen is a combination of two NRTIs and one INSTI. TLD is a fixed-dose combination of TDF 300 mg, 3TC 300 mg, and DTG 50 mg. TLD is also recommended for use as a second-line regimen for patients failing on efavirenz- or nevirapine-containing regimens or for those failing a non-DTG-containing first-line regimen. This two-page briefer provides general information for clients, clinicians, counselors, and other service providers.

ICAP webinar

Six-month Multi-month Scripting Lessons from Ethiopia, Malawi, and Zambia

ICAP, 2019

This CQUIN Learning Network webinar in innovations in differentiated service delivery highlighted six-month multi-month scripting lessons from national program scale-up in Ethiopia as well as lessons from qualitative research in Malawi and Zambia.


Optimized Supportive Care for Ebola Virus Disease: Clinical management standard operating procedures

World Health Organization (WHO), 2019

Considerable variability exists in the level of supportive care offered between Ebola treatment units (ETUs) in the same outbreak as well as across outbreaks. Building on evidence-informed guidelines created by a multidisciplinary panel of health care providers with experience in the clinical management of patients with EVD, this guidance should serve as a foundation for oSoC that should be followed to ensure both the best possible chance for survival and allow for reliable comparison of investigational therapeutic interventions as part of a randomized controlled trial. This guideline provides recommendations for the management of adults and children.

CLM Presentation

Community-Led Monitoring and Advocacy

ICAP, 2019

This presentation from the International Treatment Preparedness Coalition (ITPC) and the Network of HIV Positives in Sierra Leone (NETHIPS) provides an overview of what community-led monitoring and advocacy is, key results of ITPC's CLM, and a country perspective from Sierra Leone.

Community-led Monitoring White Paper

Community-led Monitoring of Health Services: Building Accountability for HIV Service Quality

Health GAP, 2019

The effectiveness of the HIV response is today highly variable—between populations and geographies. This paper reviews the concepts behind community-led monitoring of health services—a practice that combines systematic and routine data collection by communities with evidence-based advocacy to improve accountability, governance and quality of HIV and health services. Community-led monitoring, if effectively implemented and sufficiently resourced, can be a key intervention to correct poor retention in HIV treatment that many countries and communities are facing



OPTIONS Consortium, HP+, 2019

Governments, donors and other stakeholders in countries at the forefront of oral pre-exposure prophylaxis (PrEP) delivery have encountered several programmatic challenges such as difficulty in setting targets, tracking the continuum of PrEP delivery, and estimating program costs and impact. This Microsoft Excel-based tool is for oral PrEP implementation planning, monitoring and evaluation. PrEP-it assists with planning and monitoring via six primary functions: (1) Assesses sites’ service delivery capacity and identifies site-level bottlenecks for oral PrEP delivery; (2) Monitors program by tracking monthly PrEP initiation and continuation rates; (3) Helps with national or subnational target-setting, allowing users to generate and analyze numerical targets based on population-based coverage or service delivery capacity; (4) Forecasts drug supply needs based on targets or program implementation: (5) Estimates program costs based on targets or program implementation; and (6) Examines a program’s projected impact (number of HIV infections averted) based on targets or past delivery. Downloads include a blank worksheet and a populated, example worksheet, the PrEP-it User Guide Version 1.0 accompanies the PrEP-it tool, as well as PrEP-it: Frequently Asked Questions

WHO Policy Brief

Update of recommendations on first- and second-line antiretroviral regimens

World Health Organization (WHO), 2019

The 2019 updated guidelines provide the latest recommendations based on rapidly evolving evidence of safety and efficacy and programmatic experience using dolutegravir (DTG) and efavirenz (EFV) 400 mg in pregnant women and people coinfected with TB. These guidelines provide further reassurance of DTG as the preferred antiretroviral (ARV) drug in first- and second-line regimens due to the declining estimate of neural tube defect risk and observed efficacy. This reassurance comes at a time when pretreatment resistance to non-nucleoside reverse-transcriptase inhibitors (NNRTI) is increasing in low- and middle-income countries, creating demand for access to alternative non-NNRTI ARV drugs.

Environmental cleaning

Best Practices for Environmental Cleaning in Healthcare Facilities: in Resource-Limited Settings

Centers for Disease Control and Prevention (CDC), 2019

This document provides guidance on best practices for environmental cleaning procedures and programs in healthcare facilities in resource-limited settings. It was developed as a collaboration between the Centers for Disease Control and Prevention (CDC) and the Infection Control Africa Network (ICAN). Best Practices for Environmental Cleaning in Healthcare Facilities in Resource-Limited Settings is a publication of the Division of Healthcare Quality Promotion in the National Center for Emerging and Zoonotic Infectious Diseases within the CDC and the Education Working Group of the Infection Control Africa Network.

WHO Icon

Analysis and Use of Health Facility Data

World Health Organization, 2019

This toolkit is a set of resources to optimize the analysis and use of data collected through routine health facility information systems, also known as health management information systems (HMIS). The comprehensive toolkit includes a series of integrated modules shown below. Modules can be used individually or together, according to country needs. Each module contains a facility analysis guide with a core set of indicators and dashboards, an accompanying exercise book, and machine-readable configuration packages. Facility analysis guides can be adapted for use with different software packages. DHIS2 configuration packages are included.


Using DHIS2 Software to Track PMTCT

MEASURE Evaluation, 2019

Comprehensive guidance for developing an electronic solution using DHIS2 to track patients across the prevention of mother-to-child transmission (PMTCT) of HIV continuum of care. The goal is to increase retention of mothers and their infants through the pregnancy and breastfeeding periods, and to improve linkages to care and referrals across services. This guidance and the accompanying documentation and resources are customized to address the complexities related to the PMTCT continuum of care, but the approaches and tools presented here can provide useful learning for the development of any DHIS2 tracker.